Songfacts®:

• Drill rapper Famous Dex grew up in Chicago attending the same high school, Robeson High School, as Lil Durk. After signing with 300 Entertainment and Rich the Kid's Rich Forever label imprint, Dex released viral hits like "Drip From My Walk" and "Hit Em Wit It." The Chicago native caught the attention of the A$AP Mob, and this upbeat club banger features a couple of verses from the group's frontman, A$AP Rocky.
• Dex revealed to Complex that he wasn't keen on the song until Rocky hopped onto it.
  
  "'Pick It Up' was something very different for me. Especially getting ASAP [Rocky] on the record is a big, big look for me," Dex said. "[…] Zeke and Wayne [Famous Dex's managers] could tell you, I didn't want the song. They kept coming to me. I'm like, 'I don't like it.'"
  
  "They played it again," he continued. "Guess who is on there? ASAP Rocky. I freaked the f--k out. Oh hell nah. It sounded 10 times better and everything. It was a great, great look, and it's a great, great record. It's a great look for me and my fans. I feel like this record right here will show the world and everybody that I accomplished something. It's hard to get a track with ASAP Rocky."
• The fast-paced AWGE/Hidji Films directed visual takes place in a New Jersey flea market, as we see Dex and Rocky surrounded with beautiful women and bootleg fashions.
• The song samples Cissy Houston's 1975 track "Nothing Can Stop Me." 2 Chainz' "Stop Me Now" and Meek Mill's "Heavy Heart" also borrowed from the same song.