Songfacts®:

• Here, Jonathan Pierce sings of a lover breaking up with him as a result of the Drums frontman's infidelity. The song title is a play on the phrase "blood on his hands." It is a reference to Pierce betraying his partner through somewhere a little more, ahm, private than his hands.
• This was the track on Abysmal Thoughts that took the longest time to get right. Pierce told HMV.com:
  
  "Normally, I don't need to labour over much - and I certainly didn't with almost everything on Abysmal Thoughts, but Blood was a pain in the ass lyrically. I think over the chorus of two months, I had tried six different choruses and nothing worked. Then I went for an hour long walk near my cabin in upstate New York, and came back to the studio, sat down, and hit record with a fresh mind, and the lyrics and melody just came pouring out. So, in a way it was still effortless, but only after I put some effort into it- if that makes any sense! I def pulled that session out of the trash bin a couple times."